2-[3,5-di(trifluoromethyl)phenyl]acetonitrile

2-[3,5-di(trifluoromethyl)phenyl]acetonitrile - Names and Identifiers

Name	[3,5-bis(trifluoromethyl)phenyl]acetonitrile
Synonyms	85068-32-2 FXFFR C1CN EXFFF 3,5-DI(TRIFLUORO METHYL)BENZYL CYANIDE 3,5-BIS(TRIFLUOROMETHYL)BENZYL CYANIDE 3,5-Bis(trifluoromethyl)phenylacetonitrile 3,5-BIS(TRIFLUOROMETHYL)PHENYLACETONITRILE [3,5-bis(trifluoromethyl)phenyl]acetonitrile [3,5-Bis(trifluoromethyl)phenyl]acetonitrile (3,5-Bis(trifluoromethyl)phenyl)acetonitrile 2-[3,5-di(trifluoromethyl)phenyl]acetonitrile 2-[3,5-DI(TRIFLUOROMETHYL)PHENYL]ACETONITRILE 2-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ACETONITRILE 3,5-Bis(trifluoromethyl)benzyl cyanide, 5-(Cyanomethyl)-alpha,alpha,alpha,alpha',alpha',alpha'-hexafluoro-m-xylene
CAS	85068-32-2
EINECS	285-294-0
InChI	InChI=1/C10H5F6N/c11-9(12,13)7-3-6(1-2-17)4-8(5-7)10(14,15)16/h3-5H,1H2

2-[3,5-di(trifluoromethyl)phenyl]acetonitrile - Physico-chemical Properties

Molecular Formula	C10H5F6N
Molar Mass	253.14
Density	1.42 g/mL at 25 °C (lit.)
Boling Point	195.4±35.0 °C(Predicted)
Flash Point	>230°F
Solubility	Difficult to mix.
Vapor Presure	0.421mmHg at 25°C
Appearance	powder to lump to clear liquid
Specific Gravity	1.420
Color	White or Colorless to Light yellow
BRN	6810362
Storage Condition	2-8°C
Refractive Index	n20/D 1.4234(lit.)
MDL	MFCD00009904

2-[3,5-di(trifluoromethyl)phenyl]acetonitrile - Risk and Safety

Risk Codes	R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection
UN IDs	3276
WGK Germany	3
HS Code	29269090
Hazard Note	Corrosive
Hazard Class	6.1
Packing Group	III

2-[3,5-di(trifluoromethyl)phenyl]acetonitrile - Introduction

[3,5-bis(trifluoromethyl)phenyl]acetonitrile is an organic compound with the chemical formula C10H4F6N. It is a colorless to pale yellow crystalline powder, soluble in common organic solvents such as methanol, ethanol and ether solvents.

Regarding its properties,[3,5-bis(trifluoromethyl)phenyl]acetonitrile has a strong odor and has a higher melting point and boiling point. It is stable at room temperature, but may decompose under high temperature and light, and needs to be stored in a dry, cool, dark place.

[3,5-bis(trifluoromethyl)phenyl]acetonitrile have a wide range of uses in organic synthesis. It can be used as a reagent or catalyst for organic synthesis reactions. It can also be used to prepare compounds such as pharmaceuticals, pesticides, and high-performance polymers.

There are various methods of preparing [3,5-bis(trifluoromethyl)phenyl]acetonitrile. One common method is to react 3,5-bis (chloromethyl) benzeneacetonitrile with a trifluoromethylating reagent to obtain the product via a trifluoromethylation reaction. This reaction needs to be carried out under the protection of inert gas, and the reaction conditions are generally mild.

Regarding safety information,[3,5-bis(trifluoromethyl)phenyl]acetonitrile should be handled with attention to safety. It may be irritating and corrosive, so it is necessary to wear suitable protective equipment when operating to ensure that the operating environment is well ventilated. In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical help. Care should be taken during handling and storage to avoid contact with oxidants and flammables.

Last Update：2024-04-09 20:49:11